Dosing and Administration
How to give Comfortis® (spinosad) to your dog or cat
Safe for cats 14 weeks of age or older and 4.1 pounds of body weight or greater.
Safe for dogs 14 weeks of age or older and 5.0 pounds of body weight or greater.
One chew, every month.
Administer one tablet of Comfortis once every month to provide year-round protection. Comfortis is approved for use in cats 14 weeks of age or older and 4.1 pounds of body weight or greater. It’s safe for dogs 14 weeks of age or older and 5.0 pounds of body weight or greater. Refer to the color-coded chart below, which matches the packaging, to see the amount of active ingredient found per tablet for the corresponding weight range.
Comfortis Dosing Information
IMPORTANT SAFETY INFORMATION
For cats: The most common adverse reaction recorded in clinical trials was vomiting. Other adverse reactions were: lethargy, decreased appetite, weight loss, and diarrhea. Use with caution with concomitant extra-label use of ivermectin.
The safe use of Comfortis in breeding, pregnant, or lactating cats has not been evaluated. See Comfortis label for complete safety information.
For dogs: The most common adverse reaction reported is vomiting. Other adverse reactions reported in decreasing order of frequency are: depression/lethargy, decreased appetite, incoordination, diarrhea, itching, trembling, excessive salivation and seizures.
Following concomitant extra-label use of ivermectin with Comfortis, some dogs have experienced the following clinical signs: trembling/twitching, salivation/drooling, seizures, incoordination, excessive dilation of pupils, blindness and disorientation. Post-approval experience continues to support the safety of Comfortis when used concurrently with heartworm preventatives according to label directions.
Use with caution in breeding females and dogs with pre-existing epilepsy. The safe use of Comfortis in breeding males has not been evaluated. See Comfortis label for complete safety information.