Dosing and Administration
How to give Comfortis® (spinosad) to your dog or cat
Safe for cats 14 weeks of age or older and 2 pounds of body weight or greater.
Safe for dogs 14 weeks of age or older and 2 pounds of body weight or greater.
One chew, every month.
Administer one tablet of Comfortis once every month to provide year-round protection. Comfortis is approved for use in cats 14 weeks of age or older and 2 pounds of body weight or greater. It’s safe for dogs 14 weeks of age or older and 3.3 pounds of body weight or greater. Refer to the color-coded chart below, which matches the packaging, to see the amount of active ingredient found per tablet for the corresponding weight range.
Comfortis Dosing Information
IMPORTANT SAFETY INFORMATION
For cats: The most common adverse reaction recorded in clinical trials was vomiting. Other adverse reactions were: lethargy, decreased appetite, weight loss, and diarrhea. Use with caution with concomitant extra-label use of ivermectin.
The safe use of Comfortis in breeding, pregnant, or lactating cats has not been evaluated. See Comfortis label for complete safety information.
For dogs: The most common adverse reaction reported is vomiting. Other adverse reactions reported in decreasing order of frequency are: depression/lethargy, decreased appetite, incoordination, diarrhea, itching, trembling, excessive salivation and seizures.
Following concomitant extra-label use of ivermectin with Comfortis, some dogs have experienced the following clinical signs: trembling/twitching, salivation/drooling, seizures, incoordination, excessive dilation of pupils, blindness and disorientation. Post-approval experience continues to support the safety of Comfortis when used concurrently with heartworm preventatives according to label directions.
Use with caution in breeding females and dogs with pre-existing epilepsy. The safe use of Comfortis in breeding males has not been evaluated. See Comfortis label for complete safety information.