#1 recommended
prescription flea-only medication1,2
Learn Why
FLEA MEDICINE FOR DOGS AND CATS THAT STARTS KILLING FLEAS IN JUST 30 MINUTES
Comfortis® (spinosad) is a fast, safe and effective flea treatment for flea infestations on your dog or cat. It starts killing fleas faster than Nexgard® (afoxolaner)3,* and killed 100% of fleas on dogs and 98% of fleas on cats in just four hours in controlled laboratory studies.
*Data from two laboratory studies conducted in different locations using different dogs and strains of fleas.
The worst part of a flea infestation is not what you can see—it's what you can't. Microscopic flea eggs, larvae and pupae can permeate your home and keep the flea infestation cycle going. Comfortis kills fleas before they lay eggs and keeps killing fleas for a full month with each dose. Use Comfortis for at least three months to treat a current flea infestation, then continue routine use to prevent a re-infestation on your pet. In a field study conducted in households with existing flea infestations in dogs, flea count reductions of 97.9% were observed one month after the first treatment and 99.9% after three monthly treatments with Comfortis.4
When you want to get rid of fleas, choose Comfortis. It’s the brand trusted by veterinarians, prescribed more than 90 million times.5
Comfortis is approved for use in cats 14 weeks of age or older and 4.1 pounds of body weight or greater and dogs 14 weeks of age or older and 5.0 pounds of body weight or greater.
IMPORTANT SAFETY INFORMATION
For cats: The most common adverse reaction recorded in clinical trials was vomiting. Other adverse reactions were: lethargy, decreased appetite, weight loss, and diarrhea. Use with caution with concomitant extra-label use of ivermectin.
The safe use of Comfortis in breeding, pregnant, or lactating cats has not been evaluated. See Comfortis label for complete safety information.
For dogs: The most common adverse reaction reported is vomiting. Other adverse reactions reported in decreasing order of frequency are: depression/lethargy, decreased appetite, incoordination, diarrhea, itching, trembling, excessive salivation and seizures.
Following concomitant extra-label use of ivermectin with Comfortis, some dogs have experienced the following clinical signs: trembling/twitching, salivation/drooling, seizures, incoordination, excessive dilation of pupils, blindness and disorientation. Post-approval experience continues to support the safety of Comfortis when used concurrently with heartworm preventatives according to label directions.
Use with caution in breeding females and dogs with pre-existing epilepsy. The safe use of Comfortis in breeding males has not been evaluated. See Comfortis label for complete safety information.