Did you know?
 

Fleas are the most common external parasite of dogs and cats.

Did you know?
 

Fleas are the most common external parasite of dogs and cats.

Click to get a $25 rebate on a year's supply of Comfortis. Available by prescription from your veterinarian.

Click to get a $25 rebate on a year's supply of Comfortis. Available by prescription from your veterinarian.
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Important Safety Information

For cats: The most common adverse reaction recorded in clinical trials was vomiting. Other adverse reactions were: lethargy, decreased appetite, weight loss, and diarrhea. Use with caution with concomitant extra-label use of ivermectin.

The safe use of Comfortis in breeding, pregnant, or lactating cats has not been evaluated. See Comfortis label for complete safety information.

For dogs: The most common adverse reaction reported is vomiting. Other adverse reactions reported in decreasing order of frequency are: depression/lethargy, decreased appetite, incoordination, diarrhea, itching, trembling, excessive salivation and seizures.

Following concomitant extra-label use of ivermectin with Comfortis, some dogs have experienced the following clinical signs: trembling/twitching, salivation/ drooling, seizures, incoordination, excessive dilation of pupils, blindness and disorientation. Post-approval experience continues to support the safety of Comfortis when used concurrently with heartworm preventatives according to label directions.

Use with caution in breeding females and dogs with pre-existing epilepsy. The safe use of Comfortis in breeding males has not been evaluated.See Comfortis label for complete safety information.

References

1. Dryden, M.W., 2005 Flea Guidelines, Flea control for dogs and cats, Advanstar Veterinary Healthcare Communications, sponsored by an educational grant from Merial

2. Sousa, C.A., DVM, “Fleas, flea allergy, and flea control, a review,” Dermatology Online Journal 3(2):7, http://dermatology.cdlib.org